A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) differentially affect glutamate induced excitotoxic responses in chicken cerebellum granule neurons (CGNs) in vitro - ScienceDirect

MARCH 01, 2021

Ajay Yadav ^{a b} Steven Verhaegen ^a Evelien Verbruggen ^b Marie Kerhoas ^b Eva Henriëtte Willemijn Huiberts ^b Mussie Ghezu Hadera ^b Hanne Friis Berntsen ^{a c} Karin Elisabeth Zimmer ^d Erik Ropstad ^a Ragnhild Elisabeth Paulsen ^b

A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) enhance nerve growth factor (NGF)-induced neurite outgrowth in PC12 cells

MARCH 01, 2021

Ajay Yadav ^{a b} Mazia Amber ^c Denis Zosen ^b Nils Anders Labba ^b Eva Henriette Willemijn Huiberts ^b Johanna Samulin Erdem ^d Fred Haugen ^d Hanne Friis Berntsen ^{a d} Shanbeh Zienolddiny ^d Ragnhild Elisabeth Paulsen ^b Erik Ropstad ^a Lisa Connolly ^c Steven Verhaegen ^a

The insulin-like growth factor system: A target for endocrine disruptors?

FEBRUARY 01, 2021

Chiara Tallia, Lisa Connolly, Paul A. Fowler 

Induction of AhR transactivation by PBDD/Fs and PCDD/Fs using a novel human-relevant, high-throughput DR _human CALUX reporter gene assay

JANUARY 01, 2021

Clémence Budin ¹, Harrie Besselink ², Barbara M A van Vugt-Lussenburg ², Hai-Yen Man ², Bart van der Burg ², Abraham Brouwer ³_

Microcystins and Microcystis aeruginosa PCC7806 extracts modulate steroidogenesis differentially in the human H295R adrenal model

DECEMBER 15, 2020

Vittoria Mallia, Steven Verhaegen, Bjarne Styrishave, Gunnar Sundstøl Eriksen, Malene Louise Johannsen, Erik Ropstad, Silvio Uhlig

Targeting the aryl hydrocarbon receptor with a novel set of triarylmethanes

DECEMBER 01, 2020

Elizabeth Goya-Jorge ^{a b} Celine Rampal ^c Nicolas Loones ^c Stephen J. Barigye ^b Laureano E. Carpio ^b Rafael Gozalbes ^b Clotilde Ferroud ^c Maité Sylla-Iyarreta Veitía ^c Rosa M. Giner ^a

In vitro profiling of the potential endocrine disrupting activities affecting steroid and aryl hydrocarbon receptors of compounds and mixtures prevalent in human drinking water resources

NOVEMBER 01, 2020

Doan TQ ^a Connolly L ^b Igout A ^c Nott K ^d Muller M ^{e 1} Scippo ML ^{a 1}

Public Awareness and Risk Perceptions of Endocrine Disrupting Chemicals: A Qualitative Study

OCTOBER 23, 2020

Kelly, M.; Connolly, L.; Dean, M.

Antagonistic activity towards the androgen receptor independent from natural sex hormones in human milk samples from the Norwegian HUMIS cohort

OCTOBER 01, 2020

Bérénice Collet, Barbara M.A. van Vugt-Lussenburg, Kees Swart, Rick Helmus, Matthijs Naderman, Eva de Rijke, Merete Eggesbø, Abraham Brouwer, Bart van der Burg

In vitro differential responses of rat and human aryl hydrocarbon receptor to two distinct ligands and to different polyphenol

OCTOBER 01, 2020

T.Q. Doan ^a L. Connolly ^b A. Igout ^c M. Muller ^{d 1} M.L. Scippo ^{a 1}

Predictive modeling of aryl hydrocarbon receptor (AhR) agonism

OCTOBER 01, 2020

Elizabeth Goya-Jorge ^{a b} Rosa M. Giner ^b Maité Sylla-Iyarreta Veitía ^c Rafael Gozalbes ^a Stephen J. Barigye ^a

Calcium signaling as a possible mechanism behind increased locomotor response in zebrafish larvae exposed to a human relevant persistent organic pollutant mixture or PFOS

AUGUST 01, 2020

Maria Christou, Thomas W.K. Fraser, Vidar Berg, Erik Ropstad, Jorke H. Kamstra 

Discovery of 2-aryl and 2-pyridinylbenzothiazoles endowed with antimicrobial and aryl hydrocarbon receptor agonistic activities

AUGUST 01, 2020

Elizabeth Goya-Jorge ^{a b 1} Fatma Abdmouleh ^{c d 1} Laureano E. Carpio ^b Rosa M. Giner ^a Maité Sylla-Iyarreta Veitía ^c

Detection of high PBDD/Fs levels and dioxin-like activity in toys using a combination of GC-HRMS, rat-based and human-based DR CALUX® reporter gene assays

JULY 01, 2020

Clémence Budin, Jindrich Petrlik, Jitka Strakova, Stephan Hamm, Bjorn Beeler, Peter Behnisch, Harrie Besselink, Bart van der Burg, Abraham Brouwer 

Testing the twin testosterone transfer hypothesis—intergenerational analysis of 317 dizygotic twins born in Aberdeen, Scotland

JUNE 19, 2020

Chiara Talia1 , Edwin-Amalraj Raja2 , Sohinee Bhattacharya2 , and Paul A. Fowler1

DMSO effects larval zebrafish (Danio rerio) behavior, with additive and interaction effects when combined with positive controls

MARCH 20, 2020

Maria Christou, Arturas Kavaliauskis, Erik Ropstad, Thomas William Kenneth Fraser 

Investigation of In Vitro Endocrine Activities of Microcystis and Planktothrix Cyanobacterial Strains

FEBRUARY 27, 2020

Vittoria Mallia, ^1,2,*,Lada Ivanova ¹,Gunnar S. Eriksen ¹,Emma Harper ³,Lisa Connolly ³ and Silvio Uhlig 1

Acute Exposure to Zearalenone Disturbs Intestinal Homeostasis by Modulating the Wnt/β-Catenin Signaling Pathway

FEBRUARY 11, 2020

Tarek Lahjouji, Aurora Bertaccini, Manon Neves, Sylvie Puel, Isabelle P. Oswald, Laura Soler

Elucidating the aryl hydrocarbon receptor antagonism from a chemical-structural perspective

JANUARY 09, 2020

E. Goya-Jorge, T.Q. Doan, M.L. Scippo, M. Muller, R.M. Giner, S.J. Barigye, R. Gozalbes

Novel Microcystins from Planktothrix prolifica NIVA-CYA 544 Identified by LC-MS/MS, Functional Group Derivatization and ¹⁵N-labeling

NOVEMBER 15, 2019

Vittoria Mallia 1,2,*, Silvio Uhlig 1 , Cheryl Rafuse 3 , Juris Meija 4 and Christopher O. Miles 3

Comparative In Vitro Assessment of a Range of Commercial Feed Additives with Multiple Mycotoxin Binding Claims

NOVEMBER 12, 2019

Kolawole,  Meneely,  Greer,  Chevallier,  Jones,  Connolly,  Elliott

Human blood-based exposure levels of persistent organic pollutant (POP) mixtures antagonise androgen receptor transactivation and translocation

NOVEMBER 01, 2019

J. McComb ^a I.G. Mills ^{b g} M. Muller ^c H.F. Berntsen ^{d e} K.E. Zimmer ^f E. Ropstad ^d S. Verhaegen ^d L. Connolly ^a

A mixture of persistent organic pollutants relevant for human exposure inhibits the transactivation activity of the aryl hydrocarbon receptor in vitro

NOVEMBER 01, 2019

T.Q. Doan, H.F. Berntsen, S. Verhaegen, E. Ropstad, L. Connolly, A. Igout, M. Muller, M.L. Scippo

Human blood-based exposure levels of persistent organic pollutant (POP) mixtures antagonise androgen receptor transactivation and translocation

NOVEMBER 01, 2019

J. McComb, I.G. Mills, M. Muller, H.F. Berntsen, K.E. Zimmer, E. Ropstad, S. Verhaegen, L. Connolly

Potential adverse effects on animal health and performance caused by the addition of mineral adsorbents to feeds to reduce mycotoxin exposure

SEPTEMBER 13, 2019

Christopher T. Elliott, Lisa Connolly, Oluwatobi Kolawole

Human-Based Exposure Levels of Perfluoroalkyl Acids May Induce Harmful Effects to Health by Disrupting Major Components of Androgen Receptor Signalling In Vitro

AUGUST 21, 2019

J. McComb, I. G. Mills, Hanne Friis Berntsen, E. Ropstad, S. Verhaegen & L. Connolly

Protection against Endocrine Disruptors; detection, mixtures, health effects, effects, risk assessment and communication.

The fetal ovary exhibits temporal sensitivity to a ‘real-life’ mixture of environmental chemicals.

Effects of defined mixtures of persistent organic pollutants (pops) on multiple cellular responses in the human hepatocarcinoma cell line, hepg2, using high content analysis screening.

In vitro bioassay investigations of the endocrine disrupting potential of steviol glycosides and their metabolite steviol, components of the natural sweetener Stevia.